Synchronized Desorption Electrospray Ionization Mass Spectrometry
Journal:
Angewandte Chemie International Edition
Year:
2010
Volume:
50(11)
Page Number (starting):
2503
Page Number (ending):
2506 Keywords:
- desorption electrospray ionization;
- in situ analysis;
- mass spectrometry;
- surface analysis;
- trace analysis
Well-orchestrated: A new mass spectrometry protocol (see picture) synchronizes microdroplet creation, nebulizing gas pulsing, and DAPI interface opening. A number of advances result: 100-fold improved detection limit, simultaneous positive and negative ion spectra, and decreased spray volumes in desorption electrospray ionization (DESI).
Funding:
Office of Naval Research
DOI link:
doi:10.1002/anie.201007819 publication_user_reference: