2005-2009

2005

Ismael Cotte-Rodrίguez, Eric Handberg, Robert J. Noll,David P.A. Kilgour, and R. Graham Cooks  “Improved Detection of Low Vapor Pressure Compounds in Air by Serial Combination of Single-Sided Membrane Introduction with Fiber Introduction Mass Spectrometry (SS-MIMS-FIMS)”, Analyst130 (2005) 679-686 DOI: 10.1039/b417791f

Guangxiang Wu, R. Graham Cooks, Zheng Ouyang, “Geometry Optimization for the Cylindrical Ion Trap: Field Calculations, Simulations and Experiments”, Int. J. Mass Spectrom., 231 (2005) 119 – 132 DOI: 10.1016/j.ijms.2004.12.004

Zoltán Takáts, Ismael Cotte-Rodriguez, Nari Talaty, Huanwen Chen and R. Graham Cooks, “Direct, Trace Level Detection of Explosives on Ambient Sufaces by Desorption Electrospray Ionization Mass Spectrometry”, Chem. Commun.,15 (2005) 1950-1952 DOI: 10.1039/b418697d

Jormarie Alvarez , R. Graham Cooks, Stephan E. Barlow, Daniel J. Gaspar, Jean H. Futrell and Julia Laskin,“Preparation and in situ Characterization of Surfaces Using Soft-Landing in a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer”, Anal. Chem., 77 (2005) 3452 – 3460 DOI: 10.1021/ac0481349

Igor A. Popov, Hao Chen, Oleg N.Kharybin, Eugene N.Nikolaev and R. Graham Cooks, “Detection of Explosives on Solid Surfaces by Thermal Desorption and Ambient Ion/Molecule Reactions”, Chem. Commun., (2005) 1953-1955 DOI: 10.1039/b419291e

Ester Marotta, R. Graham Cooks and Cristina Paradisi, “Novel CFCs-substitutes recommended by EPA (hydrofluorocarbon-245fa and hydrofluoroether-7100): ion chemistry in air plasma and reactions with atmospheric ions”, J. Amer. Soc. Mass Spectrom., 16  (2005) 1081 – 1092 DOI: 10.1016/j.jasms.2005.02.021

Bogdan Gologan, Jason R. Green, Jormarie Alvarez, Julia Laskin and R. Graham Cooks, “Ion/Surface Reactions and Ion Soft-Landing”, Phys. Chem. Chem. Phys., 7 ( 2005) 1490 – 1500 DOI: 10.1039/b418056a

Brian C. Laughlin, Christopher C. Mulligan, R. Graham Cooks, “Atmospheric Pressure Ionization in a Miniature Mass Spectrometer”, Anal. Chem., 77 (2005) 2928-2939 DOI: 10.1021/ac0481708

Pengxiang Yang, R. Graham Cooks, Zheng Ouyang, Adam M. Hawkridge and David C. Muddiman, “Gentle Protein Ionization Assisted by High Velocity Gas Flow”, Anal. Chem., 77 (2005) 6174-6183 DOI: 10.1021/ac050711l

Hu, Q.; Noll,Robert J.; Li, Hongyan; Makarov, Alexander; Hardman, Mark; Cooks, R. Graham, “The Orbitrap: A New Mass Spectrometer”, J. Mass Spectrom., 40(2005) 430-443 DOI: 10.1002/jms.856

Lianming Wuand R. Graham Cooks, “Chiral and Isomeric Analysis by Electrospray Ionization and Sonic Spray Ionization Using the Fixed-Ligand Kinetic Method”,European J. Mass Spectrom., 11 (2005) 231-242 DOI: 10.1255/ejms.749

Hao Chen, Eduardo C. Meurer, Marcos N. Eberlinand R. Graham Cooks, “Hydrogen/Chlorine Exchange Reactions of Carbanions”, J. Amer. Soc. Mass Spectrom,16 (2005) 2045-2051 DOI: 10.1016/j.jasms.2005.08.012

Huanwen Chen, Ruifeng Xu,Hao Chen, R. Graham Cooksand Zheng Ouyang, “Ion/Molecule Reactions in a Miniature RIT Mass Spectrometer”, J. Mass Spectrom.40 (2005) 1403-1411 DOI: 10.1002/jms.924

Hao Chen, Dina R. Justes and R. Graham Cooks, “Proton Affinities of N-Heterocyclic Carbene Super Bases”, Org. Lett., 7 (2005) 3949-3952 DOI: 10.1021/ol0514247

Huanwen Chen, Nari N. Talaty,Zoltán Takáts,and R. Graham Cooks, “Desorption Electrospray Ionization Mass Spectrometry for High Throughput Analysis of Pharmaceutical Samples in the Ambient Environment”, Anal. Chem.,77 (2005) 6915-6927 DOI: 10.1021/ac050989d

Ismael Cotte-Rodrίguez, Zoltán Takáts, Nari Tataly, Huanwen Chen and R. Graham Cooks, “Desorption Electrospray Ionization of Explosives on Surfaces: Sensitivity and Selectivity Enhancement by Reactive Desorption Electrospray Ionization” Anal. Chem., 776755-6764 (2005) DOI: 10.1021/ac050995+

Nari Talaty, Zoltán Takáts, R. Graham Cooks, “Rapid In-Situ Detection of Alkaloids in Plant Tissue under Ambient Conditions using Desorption Electrospray Ionization”, Analyst130(2005) 1624 – 1633 DOI: 10.1039/b511161g

Justin M. Wiseman, Satu M. Puolitaival, Zoltán Takáts, R. Graham Cooks, Richard M. Caprioli, “Mass Spectrometric Profiling of Intact Biological Tissue by Using Desorption Electrospray Ionization”, Angew. Chem.,117  (2005), 7256 - 7259, [Angewandte Chemie International Edition44, 7094 –7097 (2005)] DOI: 10.1002/anie.200502362

Yishu Song, Hao Chen and R. Graham Cooks,“Reactivity of Acetonyl Anion with Nitroaromatics: An Atmospheric Pressure Chemical Ionization Study”, Rapid Commun. Mass Spectrom., 19 (2005) 3493-3499 DOI: 10.1002/rcm.2206

Takáts, J. Wiseman and R. G. Cooks, “Ambient Mass Spectrometry using Desorption Electrospray Ionization (DESI): Instrumentation, Mechanisms and Applications in Forensics, Chemistry and Biology”, J. Mass Spectrom., 40 (2005) 1261 – 1275 DOI: 10.1002/jms.922

2006

Sunnie Myung, Justin M. Wiseman, Stephen J. Valentine,Zoltán Takáts,  R. Graham Cooks, and David E. Clemmer, “Coupling Desorption Electrospray Ionization (DESI) with Ion Mobility/Mass Spectrometry for Analysis of Protein Structure: Evidence for Desorption of Folded and Denatured States” J. Phys. Chem. B., 110(2006) 5045-5051 DOI: 10.1021/jp052663e

Chao Zhang,Huanwen Chen, Andrew J. Guymon, Guangxiang Wu, R. Graham Cooks and Zheng Ouyang, “Instrumentation and Methods for Ion and Reaction Monitoring using a Non-Scanning Rectilinear Ion Trap”, Int. J. Mass Spectrom.255 (2006) 1-10 DOI: 10.1016/j.ijms.2005.10.013

Qizhi Hu, Alexander A. Makarov, R. Graham Cooksand Robert J. Noll, “Resonant AC Dipolar Excitation for Ion Motion Control in the Orbitrap Mass Analyzer”, J. Phys. Chem. A, 110 (2006) 2682 – 2689 DOI: 10.1021/jp054485v

Amy M. Tabert, Michael P. Goodwin, R. Graham Cooks, “Co-occurrence of Boundary and Resonance Ejection in a Multiplexed Rectilinear Ion Trap Mass Spectrometer”, J. Am. Soc. Mass Spectrom., 17 (2006) 56-59 DOI: 10.1016/j.jasms.2005.09.005

Tiina J. Kauppila, Justin M. Wiseman, Raimo A. Ketola, Tapio Kotiaho, R. Graham Cooks, Risto Kostiainen, ”Desorption Electrospray Ionization Mass Spectrometry for the Analysis of Pharmaceuticals and Metabolites”, Rapid Commun. Mass Spectrom., 20 (2006) 387-392 DOI: 10.1002/rcm.2304

Huanwen Chen, Zhengzheng Pan, Nari N. Talaty, R. Graham Cooks and Daniel Raftery, “Combining Desorption Electrospray Ionization Mass Spectrometry and Nuclear Magnetic Resonance for Differential Metabolomics without Sample Separation”, Rapid Commun. Mass Spectrom.,  20 (2006) 1577-1584 DOI: 10.1002/rcm.2474

Marcela Nefliu, Andre Venter and R. Graham Cooks, “Desorption Electrospray Ionization and Electrosonic Spray Ionization for Solid- and Solution-Phase Analysis of Industrial Polymers”, Chem. Commun., (2006) 888 – 890 DOI: 10.1039/b514057a

R. Graham Cooks, Hao Chen, Marcos N. Eberlin, Xubin Zhengand W. Andy Tao, “Polar Acetalization and Transacetalization in the Gas Phase: The Eberlin Reaction”,Chem. Rev., 106 (2006) 188 – 211 DOI: 10.1021/cr0400921

S. C. Nanita, R. G. Cooks, "Serine Octamer: Cluster Formation, Reactions, and Implications for Biomolecule Homochirality", Angew. Chem. Int. Ed., 45 (2006) 554-569 DOI: 10.1002/anie.200501328

Ismael Cotte-Rodrίguez, Dina Justes, Sergio Nanita, Robert Noll, and R. Graham Cooks, “Analysis of Toxic Industrial Compounds and Chemical Warfare Agents Simulants in Air and in Complex Matrices by Atmospheric Pressure Ionization Mass Spectrometry”, Analyst, 131 (2006) 579-589 DOI: 10.1039/b513605a

Qingyu Song, Sameer Kothari, Michael A. Senko, Jae C. Schwartz, Jonathan W. Amy, George C. Stafford, R. Graham Cooks, and Zheng Ouyang., "Rectilinear Ion Trap Mass Spectrometer with Atmospheric Pressure Interface and Electrospray Ionization Source", Anal. Chem.,78 (2006)718-725 DOI: 10.1021/ac0512709

Ismael Cotte-Rodríguez, Hao Chen, and R. Graham Cooks, “Rapid trace detection of triacetone triperoxide (TATP) by complexation reactions during desorption electrospray ionization”, Chem. Commun., (2006) 953 – 955 DOI: 10.1039/b515122h

Hao Chen, Ismael Cotte-Rodríguez, and R. Graham Cooks, “cis-Diol Functional Group Recognition by Reactive Desorption Electrospray Ionization (DESI)”, Chem. Commun, 6. (2006) 597-599 DOI: 10.1039/b516448f

Christopher C. Mulligan, Dina R. Justes, Robert. J. Noll, Nathaniel L. Sanders, Brian C. Laughlin and R. Graham Cooks, “Direct Monitoring of Gaseous Toxic Compounds in Air Using a Portable Mass Spectrometer”, Analyst131(2006) 556 – 567 DOI: 10.1039/b517541k

J Bogdan Gologan, Justin M. Wiseman and R. Graham Cooks, “Ion soft landing: Instrumentation and Phenomena”, in Principles of Mass Spectrometry Applied to Biomolecules, J. Laskin and Chava Lifshitz, Eds, Wiley-Interscience, (2006) 443 – 476, DOI: 10.1002/047005042

Yishu Song, Guangxiang Wu, Qingyu Song, Wolfgang R. Plass, R. Graham Cooks and Zheng Ouyang,“Novel Linear Ion Trap Mass Analyzer Composed of Four Planar Electrodes”, J. Amer. Soc. Mass Spectrom.,17(2006) 631-639 DOI: 10.1016/j.jasms.2005.12.014

Marcela Nefliu,Colin Mooreand R. Graham Cooks,Enhanced Desorption Ionization using Oxidizing Electrosprays”, J. Amer. Soc. Mass Spectrom., 17 (2006) 1091-1095 DOI: 10.1016/j.jasms.2006.04.021

Christopher C. Mulligan, Nari Talaty and R. Graham Cooks, “Desorption Electrospray Ionization with a Portable Mass Spectrometer: In-situ Analysis of Ambient Surfaces”, Chem. Commun, (2006) 1709 – 1711 DOI: 10.1039/b517357d

Amy M. Tabert, Michael P. Goodwin, Jason S. Duncan, Charles D. Fico and R. Graham Cooks, "Multiplexed Rectilinear Ion Trap Mass Spectrometer for High-Throughput Analysis", Anal. Chem.78 (2006) 4830-4838DOI: 10.1021/ac060149e

Brandy L. Young, Lianming Wu, R. G. Cooks, "Mass Spectral Methods of Chiral Analysis" ed.: Kenneth W. Busch; M. A. Busch, (2006), ch. 31.

Hao Chen, Zheng Ouyang and R. Graham Cooks,“Thermal Production and Reactions of Organic Ions at Atmospheric Pressure”, Angew. Chem.45 (2006) 3656-3660 DOI: 10.1002/anie.200600660

Rodinei Augusti, Hao Chen, Livia Schiavinato Eberlin, Marcela Nefliu and R. Graham Cooks, “Atmospheric Pressure Eberlin Transacetalization in the Heterogeneous Liquid/Gas Phase”,Int. J. Mass Spectrom., 253 (2006) 281-287 DOI: 10.1016/j.ijms.2006.05.005    

R. Graham Cooks, Zheng Ouyang, Zoltan Takats, Justin M. Wiseman, “Ambient Mass Spectrometry”, Science311  (2006) 1566-1570 DOI: 10.1126/science.1119426

Guangxiang Wu, Meng Yu, William J. Chappell, R. Graham Cooks, Wolfgang R. Plassand Zheng Ouyang, “Ion Trajectory Simulation for Electrode Configurations with Arbitrary Geometries”, J. Am. Soc. Mass Spectrom., 17 (2006) 1216-1228 DOI: 10.1016/j.jasms.2006.05.004

Guangxiang Wu, Robert J. Noll, Wolfgang R. Plass, Qizhi Hu, Richard H. Perry, and R. Graham Cooks, "Ion Trajectory Simulations of Axial AC Dipolar Excitation in the Orbitrap" Int. J. Mass Spectrom., 254 (2006) 53-62 DOI: 10.1016/j.ijms.2006.05.007

Huanwen Chen, Andre Venter and R. Graham Cooks, "Extractive electrospray ionization for direct analysis of undiluted urine, milk and other complex mixtures without sample preparation", Chem. Comm., 19 (2006) 2042-2044 DOI: 10.1039/b602614a

Zoltan Takats, Justin M. Wiseman, Demian Ifa and R. Graham Cooks, “Desorption electrospray ionization: proteomics studies by a method that bridges ESI and MALDI”, ch 6 in C. D. O'Connor and B. D. Hames (Eds.) Proteomics- Methods Express, Scion Publishing Limited, Bloxham, UK, 2008

Tiina J. Kauppila, Nari Talaty, Piia K. Salo, Tapio Kotiaho, Risto Kostiainen and R. Graham Cooks, "New Surfaces for Desorption Electrospray- Mass Spectrometry: Porous Silicon and Ultra-Thin Layer Chromatography Plates", Rapid Communications in Mass Spectrometry20 (2006) 2143-2150 DOI: 10.1002/rcm.2566

Ismael Cotte-Rodriguez and R. Graham Cooks, “Non-Proximate Detection of Explosives and Chemical Warfare Agent Simulants by Desorption Electrospray Ionization Mass Spectrometry”, Chem. Comm., 28 (2006) 2968 – 2970 DOI: 10.1039/b606020j

J. M. Wiseman, D. R. Ifa and R. Graham Cooks,  in Encyclopedia of Mass Spectrometry, M. L. Gross in “Encyclopedia of Mass Spectrometry”, M. L. Gross and Richard M. Caprioli (eds.), vol.6 Ionization Methods, “Electrosonic Spray Ionization”, pp. 494 - 497

Nari Talaty, Zoltan Takats, Justin M. Wiseman and R. Graham Cooks, in “Encyclopedia of Mass Spectrometry”, M. L. Gross and Richard M. Caprioli (eds.), vol.6 Ionization Methods, Desorption Electrospray Ionization (DESI)” pp. 579 – 591

Ouyang, P. Yang and R. Graham Cooks, in “Encyclopedia of Mass Spectrometry”, M. L. Gross and Richard M. Caprioli (eds.), vol.6 Ionization Methods, “Electrospray Iionization with Venturi and Related Devices” pp. 498 – 501

Andre Venter and R. Graham Cooks in “Encyclopedia of Mass Spectrometry”, M. L. Gross and Richard M. Caprioli (eds.), vol.6 Ionization Methods, “Extractive Electrospray Ionization” pp. 528 - 534

Andre Venter, Sara K. Poehlein, Demian R. Ifa, Anton Chin, Dan Ellison, and R. Graham Cooks, “Desorption electrospray ionization mass spectrometry study of aging products of diphenylamine stabilizer in double base propellants", Prop., Explos., Pyrotech.31 (2006) 472-476 DOI: 10.1002/prep.200600064

Pengxiang Yang, Ruifeng Xu, Sergio C. Nanita, and R. Graham Cooks, “Thermal Formation of Homochiral Serine Clusters and Implications for the Origin of Homochirality”, J. Am. Chem. Soc., 128 (2006) 17074 -17086DOI: 10.1021/ja064617d

Justin M. Wiseman, Demian R. Ifa, Qingyu Song, R. Graham Cooks, “Tissue Imaging at Atmospheric Pressure using Desorption Electrospray Ionization (DESI) Mass Spectrometry”, Angewandte Chemie 118 (2006) 7346-7350 [Angew. Chem. Int. Ed.  45 7188 – 7192 (2006), DOI:10.1002/anie.200602449] DOI:  10.1002/anie.200602449

Regina Sparrapan, Livia S. Eberlin, Renato Haddad, R. Graham Cooks, Marcos N. Eberlin and Rodinei Augusti, “Ambient Eberlin Reactions via Desorption Electrospray Ionization”, J. Mass Spectrom41 (2006) 1242-1264 DOI: 10.1002/jms.1088

Liang Gao, Qingyu Song, Garth E. Patterson, R. Graham Cooks and Zheng Ouyang, “Handheld Rectilinear Ion Trap Mass Spectrometer”, Anal. Chem., 78 (2006) 5994-6002 DOI: 10.1021/ac061144k

Yishu Song and R. Graham Cooks, “Atmospheric Pressure Ion/Molecule Reactions for the Selective Detection of Nitroaromatic Explosives using Acetonitrile and Air as Reagents”, Rapid Commun. Mass Spectrom., 20 (2006) 3130-3138 DOI: 10.1002/rcm.2714

Qizhi Hu, Nari Talaty, Robert J. Noll and R. Graham Cooks, “Desorption Electrospray Ionization (DESI) using an Orbitrap Mass Spectrometer: Exact Mass Measurements on Drugs and Peptides”, Rapid Commun. Mass Spectrom., 20 (2006) 3403-3408 DOI: 10.1002/rcm.2757

Andre Venter, Paul E. Sojka, R. Graham Cooks, “Droplet Dynamics and Ionization Mechanisms in Desorption Electrospray Ionization Mass Spectrometry”, Anal. Chem., 78  (2006) 8549-8555 DOI: 10.1021/ac0615807

2007

D. Ifa, Justin M. Wiseman, Qingyu Song and R. Graham Cooks, “Development of Capabilities for Imaging Mass Spectrometry under Ambient Conditions with Desorption Electrospray Ionization (DESI)”, Int. J. Mass Spectrom., 259 (2007) 8-15 DOI: 10.1016/j.ijms.2006.08.003

Ouyang, Z., Gao, L., Fico, M., Chappell, W. J., Noll, R. J., Cooks, R. G., “Quadrupole Ion Traps and Trap Arrays: Geometry, Material, Scale, Performance”, European J. Mass Spectrom., 13(2007) 13 -18 DOI: 10.1255/ejms.832

Scott A. Smith, Thomas A. Blake, DemianR.Ifa, R. Graham Cooks and Zheng Ouyang, “Dual-Source Mass Spectrometer with MALDI-LIT-ESI Configuration”, J. Proteome Research,6  (2007) 837-845DOI: 10.1021/pr060514i

Brandy L. Young, R. G. Cooks, Scott A. Miller, Michelle C. Madden, Michael Bair, Jingpin Jia, “Chiral Purity Assay for Flindokalner using Tandem Mass Spectrometry: Method Development, Validation, and Benchmarking", Journal of Pharmaceutical and Biomedical Analysis, 43  (2007) 1602 – 1608 DOI: 10.1016/j.jpba.2006.12.027

Sergio C. Nanita, Ewa Sokol and R. Graham Cooks, “Alkali Metal-Cationized Serine Clusters Studied by Sonic Spray Ionization Tandem Mass Spectrometry” J. Amer. Soc. Mass Spectrom., 18 (2007) 856-868 DOI: 10.1016/j.jasms.2007.01.003

Hao Chen, Livia S.Eberlin and R. Graham Cooks, “Neutral Fragment Mass Spectra after Ambient Thermal Dissociation of Peptide and Protein Ions”, J. Amer. Chem. Soc., 129   (2007)5880 -5886 DOI: 10.1021/ja067712v

Yishu Song, Nari Talaty, Andy W. Tao, Zhengzheng Pan and R. Graham Cooks, “Rapid Ambient Mass Spectrometric Profiling of Intact, Untreated Bacteria using Desorption Electrospray Ionization”, Chem. Commun., (2007) 61 – 63DOI: 10.1039/b615724f

Richard H. Perry, Chunping Wu, Marcela Nefliu and R. Graham Cooks, “Serine Sublimes with Spontaneous Chiral Amplification”, Chem. Commun.,(2007) 1071-1073DOI: 10.1039/b616196k

Julia Laskin, Peng Wang, Omar Hadjar, Jean H. Futrell, Jormarie Alvarez, and R. Graham Cooks,“Charge Retention by Peptide Ions Soft-Landed onto Self-Assembled Monolayer Surfaces”, Int. J. Mass Spectrom., 265 (2007) 237-243 DOI: 10.1016/j.ijms.2007.02.013

Liang Gao, Qingyu Song, Robert J. Noll, Jason Duncan, R. Graham Cooks and Zheng Ouyang, “Glow Discharge Electron Impact Ionization Source for Miniature Mass Spectrometers”, J. Mass Spectrom., 42 (2007) 675 – 680DOI: 10.1002/jms.1201

D. R. Ifa, L. Gumaelius, L. S. Eberlin, N. Manicke and R. G. Cooks, “Forensic Analysis of Inks by Imaging Desorption Electrospray Ionization (DESI) Mass Spectrometry”, Analyst,132  (2007) 461 – 467 DOI: 10.1039/b700236j

Qizhi Hu, R. Graham Cooks, Robert J. Noll, “Phase-Enhanced Selective Ion Ejection in an Orbitrap Mass Spectrometer”, J. Am. Soc. Mass Spectrom., 18(2007) 980-983DOI: 10.1016/j.jasms.2007.02.004

Brandy L. Young and R. Graham Cooks, “Improvements in Quantitative Chiral Determinations using the Mass Spectrometric Kinetic Method”, Int. J. Mass Spectrom.267 (2007) 199–204DOI: 10.1016/j.ijms.2007.02.036

Yishu Song and R. Graham Cooks, "Reactive Desorption Electrospray Ionization for Selective Detection of the Hydrolysis Products of Toxic Phosphonate Esters",J. Mass Spectrom.42 (2007) 1086-1092DOI: 10.1002/jms.1244

Tiina J. Kauppila, Nari Talaty, Tiia Kuuranne, Tapio Kotiaho, Risto Kostiainen and R. Graham Cooks, “Rapid Analysis of Metabolites and Drugs of Abuse from Urine Samples by Desorption Electrospray Ionization-Mass Spectrometry”, Analyst, 132(2007) 868 – 875  DOI: 10.1039/b703524a

Dina R. Justes, Nari Talaty, Ismael Cotte-Rodriguez, and R. Graham Cooks, “Detection of Explosives on Skin using Ambient Ionization Mass Spectrometry”,Chem. Commun.,(2007) 2142–2144DOI: 10.1039/b703655h

Ayanna U Jackson, Nari Talaty, R. G. Cooks and Gary J. Van Berkel “Salt Tolerance of Desorption Electrospray Ionization (DESI)”, J. Am. Soc. Mass Spectrom.,18 (2007) 2218- 2225DOI: 10.1016/j.jasms.2007.09.018

Ismael Cotte-Rodríguez, Christopher C. Mulligan, and R. Graham Cooks, "Non-Proximate Detection of Small and Large Molecules by Desorption Electrospray Ionization and Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry: Instrumentation and Applications in Forensics, Chemistry, and Biology",Anal. Chem.79 (2007) 7069-7077 DOI: 10.1021/ac0707939

Andre Venter and R. Graham Cooks, “Desorption electrospray ionization in a small pressure tight enclosure”, Anal. Chem.79 (2007) 6398-6403 DOI: 10.1021/ac0708846

Guangming Huang, Hao Chen, Xinrong Zhang, R. Graham Cooks and Zheng Ouyang  “Rapid Screening of Anabolic Steroids in Urine by Reactive Desorption Electrospray Ionization”, Anal. Chem., 79 (2007) 8327–8332 DOI: 10.1021/ac0711079

Adam Keil, Nari Talaty, Christian Janfelt, Robert J. Noll, Liang Gao, Zheng Ouyang, R Graham Cooks, “Ambient Mass Spectrometry with a Handheld Mass Spectrometer at High Pressure”, Anal. Chem., 79(2007) 7734–7739 DOI:10.1021/ac071114x

Miriam Fico, Meng Yu, Zheng Ouyang, R. Graham Cooksand William J. Chappell, “Miniaturization and Geometry Optimization of a Polymer-Based Rectilinear Ion Trap”, Anal. Chem., 79 (2007) 8076-8082 DOI: 10.1021/ac0711384

Anthony B. Costa and R. Graham Cooks, “Simulation of Atmospheric Transport and Droplet-Thin Film Collisions in Desorption Electrospray Ionization”, Chem. Commun.,(2007) 3915 – 3917 DOI: 10.1039/b710511h   

2008

Nicholas E. Manicke, Justin M. Wiseman, Demian R. Ifa and R. Graham Cooks, “Desorption Electrospray Ionization (DESI) Mass Spectrometry and Tandem Mass Spectrometry (MS/MS) of Phospholipids and Sphingolipids: Ionization, Adduct Formation and Fragmentation”, J. Am. Soc. Mass Spectrom.,19 (2008) 531–543 DOI:10.1016/j.jasms.2007.12.003.

Marcela Nefliu, Jonell N. Smith, Andre Venter and R. Graham Cooks, “Internal Energy Distributions in Desorption Electrospray Ionization (DESI)”, J. Am. Soc. Mass Spectrom., 19 (2008) 420 -427 DOI: 10.1016/j.jasms.2007.11.019

Ismael Cotte-Rodrίguez, Heriberto Hernández-Soto, Hao Chen, and R. Graham Cooks, “In-situ Trace Detection of Peroxide Explosives by Complexation during Desorption Electrospray Ionization and Desorption Atmospheric Pressure Chemical Ionization”, Anal. Chem., 80 (2008) 1512 -1519 DOI: 10.1021/ac7020085

Demian R. Ifa, Nicholas E. Manicke, Allison L. Rusine and R. Graham Cooks, “Quantitative Analysis of Small Molecules by Desorption Electrospray Ionization (DESI) Mass Spectrometry on Polytetrafluoroethylene Surfaces”, Rapid Commun. Mass Spectrom., 22 (2008) 503-510 DOI: 10.1002/rcm.3377

Justin M Wiseman, Demian R Ifa, Andre Venter and R Graham Cooks, “Ambient molecular imaging by desorption electrospray ionization mass spectrometry”,Nature Protocols, 3  (2008) 517 – 524 DOI: 10.1038/nprot.2008.11

Michael Volný, Andre Venter, Scott A. Smith, Marco Pazzi, and R. Graham Cooks, “Surface effects and Electrochemical Cell Capacitance in Desorption Electrospray Ionization”, Analyst132 (2008) 525-531 DOI: 10.1039/b717693g

Andre Venter, Marcela Nefliu, R. Graham Cooks, “Ambient Desorption Ionization Mass Spectrometry: New Methods and their Interrelationship”, Trends in Analytical Chemistry, 27 (2008) 284 -290 DOI: 10.1016/j.trac.2008.01.010   

Richard H. Perry, R. Graham Cooksand Robert J. Noll, “Orbitrap Mass Spectrometry: Instrumentation, Ion Motion and Applications”, Mass Spectrom. Rev.,27 (2008) 661 – 699, DOI: 10.1002/mas.20186

Peng, Wen-Ping; Goodwin, Mike; Nie, Zongxiu; Volny, Michael; Ouyang, Zheng; Cooks, R. G., "Ion Soft Landing using a Novel Rectilinear Ion Trap Mass Spectrometer", Anal. Chem.,   80 (2008) 6640–6649 DOI: 10.1021/ac800929w

Hao Chen, Livia S. Eberlin,  Marcela Nefliu,  Rodinei Augusti,  R. Graham Cooks, “Organic Reactions of Ionic Intermediates Promoted by Atmospheric-Pressure Thermal Activation” Angewandte Chemie International Edition47 (2008) 3422–3425 DOI: 10.1002/anie.200800072

Anthony B. Costa, R. Graham Cooks, "Simulated Splashes: Elucidating the Mechanism of Desorption Electrospray Ionization Mass Spectrometry", Chemical Physics Letters464 (2008) 1-8 DOI: 10.1016/j.cplett.2008.08.020

Tiina J. Kauppila, Nari Talaty, Ayanna U. Jackson, Tapio Kotiaho, Risto Kostiainen and R. Graham Cooks,  “Carbohydrate and steroid analysis by desorption electrospray ionization mass spectrometry”, Chemical Communications, (2008) 2674 – 2676 DOI: 10.1039/b804413a

Liang Gao, R. Graham Cooks and Zheng Ouyang, “Breaking the Pumping Speed Barrier in Mass Spectrometry: Discontinuous Atmospheric Pressure Interface”,Anal. Chem., 80 (2008) 4026 – 4032 DOI: 10.1021/ac800014v

Christian Janfelt, Nari Talaty, Christopher C. Mulligan,Adam Keil, Zheng Ouyang and R. Graham Cooks, “Mass Spectra of Proteins and Other Biomolecules Recorded using a Handheld Instrument”, Int. J. Mass Spectrom., 278 (2008)166-169 DOI: 10.1016/j.ijms.2008.04.022

Hao Chen, Livia Eberlin, Marcela Nefliu, Rodinei Augusti and R. Graham Cooks,“Organic Reactions of Ionic Intermediates Promoted by Atmospheric Pressure Thermal Activation”, Angew. Chem.Int. Ed.47 (2008) 3422 – 3425 DOI: 10.1002/anie.200800072

Demian R. Ifa, Nicholas E. Manicke, Allison L. Dill, R. Graham Cooks, “Latent Fingerprint Chemical Imaging by Mass Spectrometry”,Science,321 (2008) 805-805DOI: 10.1126/science.1157199

Nari Talaty, Christopher C. Mulligan, Dina R. Justes, Ayanna U. Jackson, Robert J. Noll and R. Graham Cooks, “Qualitative and Quantitative Analysis of Explosives and Drugs from Fabrics by Ambient Mass Spectrometry,” Analyst133 (2008) 1532-1540 DOI: 10.1039/b807934j

Ewa Sokol, Kathleen E. Edwards, Kuangnan Qian and R. Graham Cooks,“Rapid Hydrocarbon Analysis using a Miniature Rectilinear Ion Trap Mass Spectrometer”,Analyst133 (2008) 1064 – 1071 DOI: 10.1039/b805813j

Nicholas E. Manicke, Anthony B. Costa, Thomas Kistler, Demian R. Ifa, Sanket Khandelwal, R. Graham Cooks and Zheng Ouyang “Tissue Imaging by Desorption Electrospray Ionization – Mass Spectrometry and Multivariate Statistical Mapping”, Anal. Chem. in press

Lívia S. Eberlin, Yu Xia, Hao Chen and R. Graham Cooks, “Atmospheric Pressure Thermal Dissociation of Phospho- and Sulfopeptides”, J. Amer. Soc. Mass Spectrom., 19  (2008) 1897-1905DOI: 10.1016/j.jasms.2008.07.019

Liang Gao, Andy Sugiarto, Jason D. Harper, R. Graham Cooks and Zheng Ouyang, “Design and Characterization of a Multi-Source Handheld Tandem Mass Spectrometer”, Anal. Chem., 80 (2008) 7198–7205 DOI: 10.1021/ac801275x

Wen-Ping Peng, Mike Goodwin, Hao Chen, R. Graham Cooks, Jonathan Wilker, “Thermal Formation of Mixed-Metal Inorganic Complexes at Atmospheric Pressure”, Rapid Commun. Mass Spectrom22 (2008)3540-3548 DOI: 10.1002/rcm.3763

Yu Xia, Zheng Ouyang and R. Graham Cooks, “Peptide Fragmentation in Nanoelectrospray Assisted by Low Temperature Plasma Treated Surfaces”, Angew. Chem., 47 (2008) 8646 – 8649DOI: 10.1002/anie.200803477

Justin M. WisemanDemian R. IfaYongxin ZhuCandice B. KissingerNicholas E. ManickePeter T. Kissinger, and R. Graham CooksDesorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues”, Proc. Nat. Acad.  Sci. (US)105 (2008) 18120 -18125 DOI: 10.1073/pnas.0801066105

Jason D. Harper, Nicholas A. Charipar, Christopher C. Mulligan, Xinrong Zhang, R. Graham Cooks and Zheng Ouyang, "Low Temperature Plasma Probe for Ambient Desorption Ionization", Anyl. Chem., 80(2008) 9097–9104 DOI: 10.1021/ac801641a

Demian R. Ifa, Nicholas E. Manicke, Allison L. Dill and R. Graham Cooks, “Latent Fingerprint Chemical Imaging by Mass Spectrometry” Science (2008) 321 805,DOI: 10.1126/science.1157199

2009

Na Na, Yu Xia, Zhenli Zhu,Xinrong Zhang, and R. Graham Cooks, “Birch Reduction of Benzene in a Low Temperature Plasma”, Angew. Chem,48 (2009) 2017 -2019 DOI: 10.1002/anie.200805256

Nicholas E. Manicke, Thomas Kistler, Demian R. Ifa, R. Graham Cooks and Zheng Ouyang, “High ThroughputQuantitative Analysis by Desorption Electrospray Ionization Mass Spectrometry”, J. Amer. Soc. Mass Spectrom., 20 (2009) 321–325 DOI: 10.1016/j.jasms.2008.10.011

WeiXu, William J.Chappell, R. Graham Cooks and Zheng Ouyang, “Characterization of Electrode Surface Roughness and Its Impact on Ion Trap Mass Analysis”,J. Mass Spectrom., 44 (2009) 353-360 DOI: 10.1002/jms.1512

Mario Benassi, Chunping Wu, Marcela Nefliu, Demina R. Ifa, Michael Volny and R. Graham Cooks, “Redox Transformations in Desorption Electrospray Ionization”, Int. J. Mass Spectrom., 280 (2009) 235–240 DOI: 10.1016/j.ijms.2008.10.012

Zheng Ouyang and R. Graham Cooks, “Miniature Mass Spectrometers”, Ann.  Rev. Anyl. Chem., 2 (2009) 187–214 DOI: 10.1146/annurev-anchem-060908-155229.

Allison L. Dill, Demian R. Ifa, Nicholas E. Manicke, Zheng Ouyang and R. Graham Cooks, “Mass Spectrometric Imaging of Lipids using Desorption Electrospray Ionization” J. Chromatography B877 (2009) 2883–2889 DOI: 10.1016/j.jchromb.2008.12.058

Juan F. García-Reyes, Ayanna U. Jackson, Antonio Molina-Díaz and R. Graham Cooks, “Desorption Electrospray Ionization Mass Spectrometry for Trace Analyses of Agrochemicals in Food”, Anyl. Chem., 81 (2009) 820-829 DOI: 10.1021/ac802166v

Guangming Huang, Zheng Ouyang and R. Graham Cooks, “High Throughput Trace Melamine Analysis in Complex Mixtures”, Chem. Commun., (2009) 556–558 DOI: 10.1039/b818059h

Scott A. Smith, Chris C. Mulligan, Qingyu Song, Robert J. Noll, R. Graham Cooks, Zheng Ouyang, “Ion Traps for Miniature, Multiplexed and Soft Landing /technologies, ch. 2 in Ray March and John F. J. Todd (eds.)  Practical Applications of Ion Trap Mass Spectrometry, vol. IV Theory and Instrumentation, CRC Press, Boca Raton, FL, p 169 - 250

Santosh Soparawalla, Gary A. Salazar, Richard H. Perry, Mark Nicholas and R. Graham Cooks, “Pharmaceutical Cleaning Validation using Non-Proximate Large-Area Desorption Electrospray Iionization Mass Spectrometry”, Rapid Commun. Mass Spectrom., 23 (2009) 131 – 137 DOI: 10.1002/rcm.3853

Zheng Ouyang, Robert J. Noll, and R. Graham Cooks, “Handheld Miniature Ion Trap Mass Spectrometers”, Anal. Chem.,81 (2009)2421–2425 DOI: 10.1021/ac900292w

Liang Gao, Guangtao Li, Zongxiu Nie, Jason Duncan, Zheng Ouyang, R. Graham Cooks “Characterization of a Discontinuous Atmospheric Pressure Interface. Multiple Ion Introduction Pulses for Improved Performance”,International Journal of Mass Spectrometry283 (2009) 30-34 DOI: 10.1016/j.ijms.2009.01.004

Demian Ifa, Ayanna Jackson, Giuseppe Paglia, R. Graham Cooks, “Forensic Applications of Ambient Ionization Mass Spectrometry”,  Anal. Bioanal. Chem, 234(2009) 1995 - 2008 DOI: 10.1007/s00216-009-2659-2

Miriam Fico, Jeffrey D. Maas,  Scott A. Smith,  Anthony B. Costa, Zheng Ouyang, William J. Chappell, R. Graham Cooks, “Circular Arrays of Polymer-based Miniature Rectilinear Ion Traps” Analyst, 134 (2009) 1338 – 1347 DOI: 10.1039/b822140e

Richard H. Perry, Gary A. Salazar, Qizhi Hu, R. Graham Cooks and Robert J. Noll, “Rephasing Ion Packets in the Orbitrap Mass Analyzer to Improve Resolution and Peak Shape”, J. Amer. Soc. Mass Spectrom., 20 (2009) 1397-1404 DOI: 10.1016/j.jasms.2009.02.011

Zongxiu Nie, Guangtao Li, Michael P. Goodwin, Liang Gao, Jobin Cyriac and R. Graham Cooks, “In situ SIMS Analysis and Reactions of Surfaces after Soft-Landing of Mass-selected Cations and Anions in an Ion Trap Mass Spectrometer”,  J. Amer. Soc. Mass Spectrom., 20 (2009) 949 -956 DOI: 10.1016/j.jasms.2009.02.019

Ayanna U. Jackson, Alessandra Tata, Chunping Wu, George Haas, Leslie West and R. Graham Cooks, “Direct Analysis of Stevia Leaves by Desorption Electrospray Ionization Mass Spectrometry”, Analyst134 (2009) 867–874 DOI: 10.1039/b823511b

Yishu Song, Nari Talaty, Kirill Datsenko, Barry L. Wanner and R .Graham Cooks, “In VivoRecognition of Bacillus subtilis by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS)”, Analyst, (2009) 838 - 841 DOI: 10.1039/B900069K

Juan F. García-Reyes, Fabio Mazzoti, Jason D. Harper, Nicholas A. Charipar, Sheran Oradu, Zheng Ouyang, Giovanni Sindona and, R. Graham Cooks,“Direct olive oil analysis by low-temperature plasma (LTP) ambient ionization mass spectrometry”, Chem. Commun., 23 (2009) 3057-3062 DOI: 10.1002/rcm.4220

Allison L. Dill, Demian R. Ifa, Nicholas E. Manicke, Anthony B. Costa, José A.  Ramos-Vara, Deborah W. Knapp and R. Graham Cooks, “Lipid Profiles of Canine Invasive Transitional Cell Carcinoma of the Urinary Bladder and Adjacent Normal Tissue by Desorption Electrospray Ionization Imaging Mass Spectrometry”, Anal. Chem., 81 (2009) 8758 – 8764 DOI: 10.1021/ac901028b

Liang Gao, Guangtao Li, Jobin Cyriac, Zongxiu Nie, R. Graham Cooks, “Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry”, J. Phys. Chem. C, (2009) 114, 5331–5337 DOI: 10.1021/jp904960t

Nathaniel L. Sanders, Ewa Sokol, Richard H. Perry, Guangming Huang, Robert J. Noll, Jason S. Duncan, R. Graham Cooks,  “Handheld Mass Spectrometer for Environmentally Relevant Analytes Using a Variety of Sampling and Ionization Methods”, Eur. J. Mass Spectrom.,15(2009) DOI: 10.1255/ejms.1036

Yu Xia; R. Graham Cooks, “Cleavage of Disulfide Bonds in PolypeptidesInduced by Hydroxyl Radical Addition”, J. Am. Chem. Soc., 2009 DOI: 10.1016.jacs.2009.08.019

Nicholas Manicke, Marcela Nefliu, Chunping Wu, John Woods, Vladimir Reiser, Ronald Hendrickson and R. Graham Cooks, "Imaging of Lipids in Atheroma by Desorption Electrospray Ionization Mass Spectrometry", Anal. Chem., 81 (2009) 8702- 8707 DOI: 10.1021/ac901739s

Chunping Wu, Kuangnan Qian, Marcela Nefliu and R. Graham Cooks, “Ambient Analysis of Saturated Hydrocarbons using Discharge-induced Oxidation in Desorption Electrospray Ionization”, J. Am. Chem. Soc. Mass Spectrom,  (2009) DOI: 10.1016/j.jasms.2009.10.006

Livia S. Eberlin, Demian R. Ifa, Chunping Wu and R. Graham Cooks, Three-Dimensional Molecular Imaging of Mouse Brain by Lipid Analysis using Ambient Ionization Mass Spectrometry”,Angew. Chem. Int. Ed., 48 (2009), 1-5, DOI: 10.1002/anie.200906283

Qingyu Song, Wei Xu, Scott A. Smith, Liang Gao, William J. Chappell, R. Graham Cooks, Zheng Ouyang, "Ion trap mass analysis at high pressure: an experimental characterization", Journal of Mass Spectrometry, (2009)45, 26-34   DOI: 10.1002/jms.1684

He Wang, Jiangjiang Liu, R. Graham Cooks, Zheng Ouyang, "Paper Spray for Direct Analysis of Complex Mixtures using Mass Spectrometry", Angewandte Chemie International Edition, (2009) 49, 877-880.   DOI: 10.1002/anie.200906314

Allison Dill, Demian R. Ifa, Nicholas E. Manicke, Anthony B. Costa, Jose A. Vara-Romeros, Deborah Knapp, Graham Cooks, “Lipid Profiles of Canine Invasive Transitional Cell Carcinoma of the Urinary Bladder and Adjacent Normal Tissue by Desorption Electrospray Ionization Imaging Mass Spectrometry”, Anal. Chem.,81(2009), 8758-8764 DOI: 10.1021/ac901028b

Liang Gao, Guangtao Li, Jobin Cyriac, Zongxiu Nie, R. Graham Cooks, “Imaging of Surface Charge and the Mechanism of Desorption Electrospray Ionization Mass Spectrometry”, J. Phys. Chem. C, (2009) 114, 5331–5337 DOI: 10.1021/jp904960t