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Professional Information

Conference Presentations
  • 56th ASMS Conference, Denver, CO, 2008: "Direct Analysis of Intact and Oxidized Phospholipids and Sphingolipids in Tissue Samples by Desorption Electrospray Ionization Mass Spectrometry" M Nefliu, NE Manicke, RG Cooks
  • 56th ASMS Conference, Denver, CO, 2008: "Development of a High Throughput Screening Method for the Detection of Glycosylated Flavonoids by GI-DESI" AU Jackson, M Nefliu, SR Werner, S Oradu, JA Morgan, RG Cooks
  • 55th ASMS Conference, Indianapolis, IN, 2007: "Online MS Investigation of Chiral Amplification of Amino Acids Sublimates" M Nefliu, RH Perry, C Wu, S Bird, DE Clemmer, RG Cooks.
  • 55th ASMS Conference, Indianapolis, IN, 2007: "Internal Energy Distribution of Ions Produced in DESI and the Influence of Source Parameters on Internal Energy" J Smith, M Nefliu, A Venter, RG Cooks
  • Turkey Run Analytical Chemistry Conference, Indianapolis, IN, Oct. 2006: "Energetics of the DESI Process" M Nefliu, RG Cooks.
  • 54th ASMS Conference, Seattle, WA, 2006: "Desorption Electrospray Ionization and Electrosonic Spray Ionization for Solid- and Solution-Phase Analysis of Industrial Polymers" M Nefliu, A Venter, RG Cooks.
Research Interests
  • Atmospheric pressure ionization mass spectrometry (API-MS)
  • Desorption electrospray ionization (DESI) - fundamentals and applications
  • Atmospheric pressure ion/molecule reactions
  • Non-covalent clustering of amino acids
Education
  • Purdue University, PhD Student, 2004-present
  • Bucharest University, Romania, M.S. Chemistry
  • Bucharest University, Romania, B.S. Chemistry
Honors and Awards
  • ACS-DAC Fellowship, Purdue University, 2008 summer
  • Schering Plough Science and Innovation Award, Purdue University, 2008
  • Robert R. Squires Scholar (for outstanding fundamental research), Purdue University, 2006-2007

Publications

  1. Marcela Nefliu, Andre Venter, R. Graham Cooks, "Desorption electrospray ionization and electrosonic spray ionization for solid- and solution-phase analysis of industrial polymers" , Chemical Communications , 2006 , 888 -890, doi: 10.1039/b514057a
  2. Marcela Nefliu, Colin Moore, and R. Graham Cooks, "Enhanced Desorption Ionization using Oxidizing Electrosprays" , Journal of the American Society of Mass Spectrometry , 2006 , 17(8), 1091 doi: 10.1016/j.jasms.2006.04.021
  3. Rodinei Augusti, Hao Chen, Livia Schiavinato Eberlin, Marcela Nefliu and R. Graham Cooks, "Atmospheric pressure Eberlin transacetalization reactions in the heterogeneous liquid/gas phase" , International Journal of Mass Spectrometry , 2006 , 253, 281 -287, doi: 10.1016/j.ijms.2006.05.005
  4. Perry, R. H., Wu, C., Nefliu, M., and Cooks, R. G., "Serine Sublimes with Spontaneous Chiral Amplification" , Chemical Communications , 2007 , 1071 -1073, doi: 10.1039/b616196k
  5. Marcela Nefliu, Jonell N. Smith, Andre Venter, and R. Graham Cooks, "Internal Energy Distributions in Desorption Electrospray Ionization (DESI)" , Journal of the American Society of Mass Spectrometry , 2008 , 19, 420 -427, http://dx.doi.org/10.1016/j.jasms.2007.11.019
  6. Andre Venter, Marcela Nefliu, R. Graham Cooks, "Ambient Desorption Ionization Mass Spectrometry" , Trends in Analytical Chemistry , 2008 , 27, 284 -290, doi:10.1016/j.trac.2008.01.010
  7. H. Chen, L. S. Eberlin, M. Nefliu, R. Augusti, R. G. Cooks, "Organic Reactions of Ionic Intermediates Promoted by Atmospheric-Pressure Thermal Activation" , Angewandte Chemie International Edition , 2008 , 47, 3422 -3425, DOI: 10.1002/anie.200800072
  8. Mario Benassi, Chunping Wu, Marcela Nefliu, Demian Ifa, Michael Volny, R. Graham Cooks , "Redox transformations in Desorption Electrospray Ionization" , International Journal of Mass Spectrometry , 2009 , 280, 235 -240, 10.1016/j.ijms.2008.10.012
  9. Ayanna U. Jackson, Marcela Nefliu, Sean R. Werner, Sheran Oradu, John A. Morgan, R. Graham Cooks , "Development of a high throughput screening method for the detection of glycosylated flavonoids by GI-DESI" , 2008 , in preparation,
  10. Nicholas E. Manicke, Marcela Nefliu, Chunping Wu, John W. Woods, Vladimir Reiser, Ronald C. Hendrickson, R. Graham Cooks, "Imaging of Lipids in Atheroma by Desorption Electrospray Ionization Mass Spectrometry " , Analytical Chemistry , 2009 , in press, doi: 10.1021/ac901739s
  11. Chunping Wu, Kuangnan Qian, Marcela Nefliu, R. Graham Cooks, "Ambient Analysis of Saturated Hydrocarbons using Discharge-induced Oxidation in Desorption Electrospray Ionization" , Journal of the American Society of Mass Spectrometry , 2009 , doi:10.1016/j.jasms.2009.10.006