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Professional Information

Conference Presentations
  • 57th ASMS Conference on Mass Spectrometry, 2009. "Quantitation of Drugs in Biological Matrices by Desorption Electrospray Ionization: Accuracy, Precision, Dynamic Range and Limit of Detection"
  • 57th ASMS Conference on Mass Spectrometry, 2009. "Tissue Imaging Using Simultaneous Chemical Derivatization and Desorption Electrospray Ionization"
  • 56th ASMS Conference on Mass Spectrometry, 2008. "Automated Collection and Analysis of Desorption Electrospray Ionization (DESI) Mass Spectrometry Imaging Data"
  • 56th ASMS Conference on Mass Spectrometry, 2008. "Direct Analysis of Intact and Oxidized Phospholipids and Sphingolipids in Tissue Samples by Desorption Electrospray Ionization Mass Spectrometry"
  • 18th Sanibel Conference on Mass Spectrometry, 2007. "Forensic analysis of inks by imaging desorption electrospray ionization (DESI) mass spectrometry"
  • 55th ASMS Conference on Mass Spectrometry, 2007. "Desorption Electrospray Ionization (DESI) Mass Spectrometry and Tandem Mass Spectrometry (MS/MS) of Lipids: Ionization, Adduct Formation and Fragmentation"
  • 55th ASMS Conference on Mass Spectrometry, 2007. "Analysis of Latent Fingerprints by Imaging Desorption Electrospray Ionization (DESI) - Mass Spectrometry"
  • 54th ASMS Conference on Mass Spectrometry, 2006. "Reactive Desorption Electrospray Ionization Mass Spectrometry (R-DESI) of Proteins and Peptides"
Research Interests
  • Biochemical applications of electrospray ionization and desorption electrospray ionization
Education
  • B.S., Biochemistry, University of Evansville, 2004
Honors and Awards
  • Merck Research Laboratories Fellowship in Analytical/Physical Chemistry, 2008
  • East Asia and Pacific Summer Institutes for U.S. Graduate Students (EAPSI) Fellowship, 2008
  • Andrews Fellowship, Purdue University 2006
  • Ross Fellowship, Purdue University, 2005
  • Goldwater Scholar, 2003

Publications

  1. Demian R Ifa, Luke Gumaelius, Livia S Eberlin, Nicholas E Manicke and R Graham Cooks, "Forensic Analysis of Inks by Imaging Desorption Electrospray Ionization (DESI) Mass Spectrometry" , Analyst , 2007 , 132, 461 -467, doi:10.1039/b700236j
  2. Demian R Ifa, Nicholas E Manicke, Allison L Rusine and R Graham Cooks, "Quantitative Analysis of Small Molecules by Desorption Electrospray Ionization (DESI) Mass Spectrometry from PTFE surfaces" , Rapid Communications in Mass Spectrometry , 2008 , 22, 503 -510, doi: 10.1002/rcm.3377
  3. Nicholas E. Manicke, Justin M. Wiseman, Demian R. Ifa, R. Graham Cooks, "Desorption Electrospray Ionization (DESI) Mass Spectrometry and Tandem Mass Spectrometry (MS/MS) of Phospholipids and Sphingolipids: Ionization, Adduct Formation, and Fragmentation" , Journal of the American Society of Mass Spectrometry , 2008 , 19, 531 -543,
  4. Demian R Ifa, Nicholas E Manicke, Allison L Dill and R Graham Cooks, "Latent Fingerprint Chemical Imaging by Mass Spectrometry" , Science , 2008 , 321, 805 -805, doi: 10.1126/science.1157199 (Full Text)
  5. Justin M. Wiseman, Demian R. Ifa, Yongxin Zhu, Candice B. Kissinger, Nicholas E. Manicke, Peter T. Kissinger and R. Graham Cooks, "Desorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues" , Proceedings of the National Academy of Sciences , 2008 , 105(47), 18120 -18125, doi:10.1073/pnas.0801066105
  6. Nicholas E. Manicke, Thomas Kistler, Demian R. Ifa, R. Graham Cooks, Zheng Ouyang, "High-Throughput Quantitative Analysis by Desorption Electrospray Ionization Mass Spectrometry" , Journal of the American Society of Mass Spectrometry , 2009 , 20, 321 -325, doi:10.1016/j.jasms.2008.10.011
  7. Allison L. Dill, Demian R. Ifa, Nicholas E. Manicke, Zheng Ouyang, R. Graham Cooks, "Mass Spectrometric Imaging of Lipids Using Desorption Electrospray Ionization" , Journal of Chromatography B , 2009 , 877, 2882 -2889, doi:10.1016/j.jchromb.2008.12.058
  8. Chunping Wu, Demian R. Ifa, Nicholas E. Manicke, R. Graham Cooks, "Rapid, Direct Analysis of Cholesterol by Charge Labeling in Reactive Desorption Electrospray Ionization" , Analytical Chemistry , 2009 , 81, 7618 -7624, DOI: 10.1021/ac901003u
  9. Allison L. Dill, Demian R. Ifa, Nicholas E. Manicke, Anthony B. Costa, Jose A. Ramos Vara, Deborah W. Knapp, R. Graham Cooks, "Lipid Profiles of Canine Invasive Transitional Cell Carcinoma of the Urinary Bladder and Adjacent Normal Tissue by Desorption Electrospray Ionization Imaging Mass Spectrometry" , Analytical Chemistry , 2009 , 81, 8758 -8764, doi: 10.1021/ac901028b
  10. Nicholas E. Manicke, Marcela Nefliu, Chunping Wu, John W. Woods, Vladimir Reiser, Ronald C. Hendrickson, R. Graham Cooks, "Imaging of Lipids in Atheroma by Desorption Electrospray Ionization Mass Spectrometry " , Analytical Chemistry , 2009 , in press, doi: 10.1021/ac901739s
  11. Chunping Wu, Demian R. Ifa, Nicholas E. Manicke and R. Graham Cooks, "Molecular Imaging of Adrenal Gland by Desorption Electrospray Ionization Mass spectrometry" , Analyst , 2010 , doi:10.1039/b919816d