Instrumentation

High-throughput Reaction Screening and Bioassays

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Ionization Sources

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Mass Spectrometers

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3D Printer

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Historical Instrumentation in Aston Labs:

BEEQ (1992)

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Reversed geometry “MIKES” instrument 
R.W. Kondrat, G.A. McClusky and R.G. Cooks, "Direct Mass Spectrometric Mixture Analysis by Negative Ion MIKES", Anal. Chem., 50 (8) (1978) 1222,doi: 10.1021/ac50030a054

Miniature mass spectrometers 
Zheng Ouyang and R. Graham Cooks, "Miniature Mass Spectrometers", Annual Review of Analytical Chemistry, 2009, 2, 187-214, doi: 10.1146/annurev-anchem-060908- 155229

Hybrid mass spectrometers    
G.L. Glish, S.A. McLuckey, T.Y. Ridley and R.G. Cooks, "A New 'Hybrid' Sector/Quadrupole Mass Spectrometer for Mass Spectrometry/Mass Spectrometry", Int. J. Mass Spectrom. Ion Phys., 41 (1982) 157-177, doi: 10.1016/0020-7381(82)85032-8

Ion trap for MS/MS 
J.N. Louris, R.G. Cooks, J.E.P. Syka, P.E. Kelley, G.C. Stafford and J.F.J. Todd, "Instrumentation, Applications and Energy Deposition in Quadrupole Ion Trap MS/MS Spectrometry", Anal. Chem., 59 (1987) 1677-1685, doi: 10.1021/ac00140a021

Surface induced dissociation (QQ) instrument

Bioreactor monitoring instrumentation  
N. Srinivasan, N. Kasthurikrishnan, R. G. Cooks, M. S. Krishnan and G. T. Tsao, "On- Line Monitoring with Feedback Control of Bioreactors using a High Ethanol Tolerance Yeast by Membrane Introduction Mass Spectrometry", Anal. Chim. Acta, 316 (1995), 269-276, doi: 10.1016/0003-2670(95)00362-4

Ion surface scattering spectrometer (BEEQ) for collision dynamics

High and low energy collision instrumentation     
A.E. Schoen, J.W. Amy, J.D. Ciupek, R.G. Cooks, P. Dobberstein and G. Jung, "A Hybrid BEQQ Mass Spectrometer", Int. J. Mass Spectrom. Ion Proc., 65 (1985) 125-140, doi: 10.1016/0168-1176(85)85059-X

ITSIM program for simulating ion behavior in ion traps –  widely distributed  
R. K. Julian, M. Nappi, C. Weil and R.G. Cooks, "Multi-Particle Simulation in the Ion Trap Mass Spectrometer: Resonant and DC Pulse Excitation", J. Am. Soc. Mass Spectrom., 6 (1995) 57, doi: 10.1016/1044-0305(94)00087-G