2015-2019

2015

Soumabha Bag, P.I. Hendricks, J.C. Reynolds and R.G. Cooks, “Biogenic aldehyde determination by reactive paper spray ionization mass spectrometry”, Anal. Chim. Acta., 860 (2015) 37-42 DOI:10.1016/j.aca.2015.01.007

K. S. Kerian, A. K. Jarmusch, V. Pirro, M. O. Koch, T. A. Masterson, L. Cheng and R. G. Cooks, “Differentiation of prostate cancer from normal tissue in radical prostatectomy specimens by desorption electrospray ionization and touch spray ionization mass spectrometry”, Analyst., 140 (2015) 1090-1098 DOI: 10.1039/C4AN02039A

Valentina Pirro, Alan K. Jarmusch, Marco Vincenti and R. Graham Cooks, “Direct drug analysis from oral fluid using medical swab touch spray mass spectrometry”, Anal. Chim. Acta., 861 (2015) 47-54 DOI:10.1016/j.aca.2015.01.008

R. Graham Cooks, Alan K. Jarmusch, Christina R. Ferreira and Valentina Pirro, “Skin molecule maps using mass spectrometry”, PNAS., 112 (2015) 5261-5262 DOI: 10.1073/pnas.1505313112

Anyin Li, Adam Hollerbach, Qingjie Luo and R. Graham Cooks, “On-Demand Ambient Ionization of Picoliter Samples Using Charge Pulses”, Angew. Chem. Int. Ed., 54 (2015) 6893-6895 DOI 10.1002/anie.201501895

Michael Wleklinski, Yafeng Li, Soumabha Bag, Depanjan Sarkar, Rahul Narayanan, T. Pradeep, and R. Graham Cooks, “Zero Volt Paper Spray Ionization and Its Mechanism”, Anal. Chem., 87 (2015) 6786-6793 DOI: 10.1021/acs.analchem.5b01225

Michael Wleklinski, Depanjan Sarkar, Adam Hollerbach, Thalappil Pradeep and R. Graham Cooks, “Ambient preparation and reactions of gas phase silver cluster cations and anions”, Phys. Chem. Chem. Phys., 17 (2015) 18364-18373 DOI: 10.1039/C5CP01538C

Qiang Ma, Hua Bai, Wentao Li, Chao Wang, R. Graham Cooks and Zheng Ouyang, “Rapid analysis of synthetic cannabinoids using a miniature mass spectrometer with ambient ionization capability”, Talanta., 142 (2015) 190-196 DOI:10.1016/j.talanta.2015.04.044

Chien-Hsun Chen, Ziqing Lin, Ran Tian, Riyi Shi, R. Graham Cooks and Zheng Ouyang, “Real-Time Sample Analysis Using a Sampling Probe and Miniature Mass Spectrometer”, Anal. Chem., 87 (2015) 8867-8873 DOI: 10.1021/acs.analchem.5b01943

Alan K. Jarmusch, Kevin S. Kerian, Valentina Pirro, Tyler Peat, Craig A. Thompson, José A. Ramos-Vara, Michael O. Childress and R. Graham Cooks, “Characteristic lipid profiles of canine non-Hodgkin's lymphoma from surgical biopsy tissue sections and fine needle aspirate smears by desorption electrospray ionization – mass spectrometry”, Analyst., 140 (2015) 6321-6329 DOI: 10.1039/C5AN00825E

Fred P. M. Jjunju, Simon Maher, Anyin Li, Sarfaraz U. Syed, Barry Smith, Ron M. A. Heeren, Stephen Taylor and R. Graham Cooks, “Hand-Held Portable Desorption Atmospheric Pressure Chemical Ionization Ion Source for in Situ Analysis of Nitroaromatic Explosives”, Anal. Chem., 87 (2015) 10047-10055 DOI: 10.1021/acs.analchem.5b02684

Rahul Narayanan, Depanjan Sarkar, Anirban Som, Michael Wleklinski, R. Graham Cooks, and Thalappil Pradeep, “Anisotropic Molecular Ionization at 1 V from Tellurium Nanowires (Te NWs)”, Anal. Chem., 87 (2015) 10792-10798 DOI: 10.1021/acs.analchem.5b01596

Ryan M. Bain, Christopher J. Pulliam, Shannon A. Raab and R. Graham Cooks, “On-Line Synthesis and Analysis by Mass Spectrometry”, J. Chem. Educ., 92 (2015) 2146-2151 DOI: 10.1021/acs.jchemed.5b00165

Pengyuan Liu, R. Graham Cooks and Hao Chen, “Nuclear Magnetic Resonance Structure Elucidation of Peptide b2 Ions”, Angew. Chem. Int. Ed., 54 (2015) 1547-1550 DOI 10.1002/anie.201410250

Fred P. M. Jjunju, Simon Maher, Anyin Li, Abraham K. Badu-Tawiah, Stephen Taylor and R. Graham Cooks, “Analysis of Polycyclic Aromatic Hydrocarbons Using Desorption Atmospheric Pressure Chemical Ionization Coupled to a Portable Mass Spectrometer”, JASMS., 26 (2015) 271-280 DOI:10.1007/s13361-014-1029-2

Chien-Hsun Chen, Tsung-Chi Chen, Xiaoyu Zhou, Robert Kline-Schoder, Paul Sorensen, R. Graham Cooks and Zheng Ouyang, “Design of Portable Mass Spectrometers with Handheld Probes: Aspects of the Sampling and Miniature Pumping Systems”, JASMS., 26 (2015) 240-247 DOI: 10.1007/s13361-014-1026-5

Christopher J. Pulliam, Ryan M. Bain, Joshua S. Wiley, Zheng Ouyang and R. Graham Cooks, “Mass Spectrometry in the Home and Garden”, JASMS., 26 (2015) 224-230 DOI: 10.1007/s13361-014-1056-z

R. Graham Cooks, Alan K. Jarmusch and Michael Wleklinski, “Direct analysis of complex mixtures by mass spectrometry”, Int.. J. Mass Spectrom., 377 (2015) 709-718 DOI:10.1016/j.ijms.2014.06.035

Zane Baird, Pu Weia and R. Graham Cooks, “Ion creation, ion focusing, ion/molecule reactions, ion separation, and ion detection in the open air in a small plastic device”, Analyst., 140 (2015) 696-700 DOI: 10.1039/C4AN01929F

Ahmed M. Hamid, Pu Wei, Alan K. Jarmusch, Valentina Pirro and R.Graham Cooks, “Discrimination of Candida species by paper spray mass spectrometry”, Int.. J. Mass Spectrom., 378 (2015) 288-293 DOI:10.1016/j.ijms.2014.09.013

Ryan M. Bain, Christopher J. Pulliama and R. Graham Cooks, “Accelerated Hantzsch electrospray synthesis with temporal control of reaction intermediates”, Chem. Sci., 6 (2015) 397-401 DOI: 10.1039/C4SC02436B

Christina R. Ferreira, Alan K. Jarmusch, Valentina Pirro, Clint M. Alfaro, Andres F. González-Serrano, Heiner Niemann, Matthew B. Wheeler, Rathnaweera A. C. Rabel, Judy E. Hallett, Rebecca Houser, Annemarie Kaufman and R. Graham Cooks, “Ambient ionisation mass spectrometry for lipid profiling and structural analysis of mammalian oocytes, preimplantation embryos and stem cells”, Reprod. Fertil. Dev., 27 (2015) 621-637 DOI: 10.1071/RD14310

Michael Wleklinski, Depanjan Sarkar, T. Pradeep and R. Graham Cooks, “Synthesis and Reactions of Atomically Precise Clusters at Atmospheric Pressure”, JMS., 50 (2015) 2-3 DOI: 10.1002/jms.3511

2016

V. Pirro, S. C. Guffey, M. S. Sepúlveda, C. T. Mahapatra, C. R. Ferreira, A. K. Jarmusch and R. G. Cooks “Lipid dynamics in zebrafish embryonic development observed by DESI-MS imaging and nanoelectrospray-MS” Mol. BioSyst., 12 (2016) 2069–2079 DOI:10.1039/C6MB00168H

Clint M. Alfaro, Alan K. Jarmusch, Valentina Pirro, Kevin S. Kerian, Timothy A. Masterson, Liang Cheng and R. G. Cooks “Ambient ionization mass spectrometric analysis of human surgical specimens to distinguish renal cell carcinoma from healthy renal tissue” Analytical and Bioanalytical Chemistry, 408 (2016) 5407–5414 https://doi.org/10.1007/s00216-016-9627-4

Alan K. Jarmusch, Clint M. Alfaro, Valentina Pirro, Eyas M. Hattab, Aaron A. Cohen-Gado and R. G. Cooks “Differential Lipid Profiles of Normal Human Brain Matter and Gliomas by Positive and Negative Mode Desorption Electrospray Ionization – Mass Spectrometry Imaging” PLoS One, 11 (2016) DOI::10.1371/journal.pone.0163180

Christina R. Ferreira, Karen E. Yannell, Brit Mollenhauer, Ryan D. Espy, Fernanda B. Cordeiro, Z. Ouyang and R. G. Cooks “Chemical profiling of cerebrospinal fluid by multiple reaction monitoring mass spectrometry” Analyst, 141 (2016) 5252–5255 DOI:10.1039/C6AN01618A

Michael Wleklinski, Caitlin E. Falcone, Bradley P. Loren, Zinia Jaman, Kiran Iyer, Samuel H. Ewan, Seok-Hee Hyun, David H. Thompson, R. Graham Cooks, "Can Accelerated Reactions in Droplets Guide Chemistry at Scale?" Eur. J. Org. Chem., 5480-5484 (2016) DOI: 10.1002/ejoc.201601270

Dalton T. Snyder, Christopher J. Pulliam and R. Graham Cooks, “Single analyzer precursor scans using an ion trap” Rapid Commun. Mass Spectrom., 30 (2016) 800–804 DOI: 10.1002/rcm.7500

Dalton Snyder, Christopher J. Pulliam, and R. Graham Cooks “Extending the mass range of a miniature ion trap mass spectrometer using the inverse Mathieu q scan”, International Journal of Mass Spectrometry,  (2016) DOI: http://dx.doi.org/10.1016/j.ijms.2016.10.022

Dalton Snyder and R. Graham Cooks “Ion isolation and multigenerational collision-induced dissociation using the inverse Mathieu q scan”, Rapid Communications in Mass Spectrometry,  (2016) DOI: 10.1002/rcm.7782

Dalton Snyder and R. Graham Cooks “Multigenerational Broadband Collision-Induced Dissociation of Precursor Ions in a Linear Quadrupole Ion Trap”, J. Am. Soc. Mass Spectrom.,  (2016) DOI: 10.1007/s13361-016-1493-y

Dalton Snyder, Christopher J. Pulliam, and R. Graham Cooks “Linear mass scans in quadrupole ion traps using the inverse Mathieu q scan”, Rapid Commun. Mass Spectrom.,  (2016) DOI: 10.1002/rcm.7710

Dalton Snyder, Patrick Fedick, and R. Graham Cooks “Multigenerational Collision-Induced Dissociation for Characterization of Organic Compounds”, Anal. Chem.,  (2016) DOI: 10.1021/acs.analchem.6b02209

Dalton Snyder and R. Graham Cooks “Ion Isolation in a Linear Ion Trap Using Dual Resonance Frequencies”, J. Am. Soc. Mass Spectrom.,  (2016) DOI: 10.1007/s13361-016-1494-x

Dalton Snyder and R. Graham Cooks “Successive Resonances for Ion Ejection at Arbitrary Frequencies in an Ion Trap”, J. Am. Soc. Mass Spectrom.,  (2016) DOI: 10.1007/s13361-016-1473-2

Dalton T. Snyder, Christopher J. Pulliam, Joshua S. Wiley, Jason Duncan, and R. Graham Cooks “Experimental Characterization of Secular Frequency Scanning in Ion Trap Mass Spectrometers”, J. Am. Soc. Mass Spectrom., 27 (2016) 1243 - 1255 DOI: 10.1007/s13361-016-1377-1

Dalton T. Snyder, Christopher J. Pulliam and R. Graham Cooks, “Calibration procedure for secular frequency scanning in ion trap mass spectrometers” Rapid Commun. Mass Spectrom., 30 (2016) 1190–1196 DOI: 10.1002/rcm.7550

Xin Yan, Ryan Bain, and R. Graham Cooks “Organic Reactions in Microdroplets: Reaction Acceleration Revealed by Mass Spectrometry”, Angew. Chem. Int. Ed., 55 (2016) 12960-12972 DOI: 10.1002/anie.201602270

Xin Yan, Ryan M. Bain, and R. Graham Cooks “Organic Reactions in Microdroplets: Reaction Acceleration Revealed by Mass Spectrometry”, Angew. Chem. Int. Ed., 55 (2016) DOI: 10.1002/anie.201602270

Stephen Ayrton, R. Graham Cooks, and Michael Pugia, “Molecular labels for analysis of amines and diols by spray based ionization-mass spectrometry”, Analyst, 141 (2016) 5398-5403 DOI:  10.1039/c6an00907g

Ryan M. Bain, Christopher J. Pulliam, Fabien Thery, and R. Graham Cooks, “Accelerated Chemical Reactions and Organic Synthesis in Leidenfrost Droplets”, Angew. Chem. Int. Ed., 55 (2016) 10478–10482 DOI: 10.1002/anie.201605899

Ryan M. Bain, Christopher J. Pulliam, Stephen T. Ayrton, Kinsey Bain, and R. Graham Cooks, “Accelerated hydrazone formation in charged microdroplets”, Rapid Commun. Mass Spectrom. , 30 (2016) 1875 - 1878 DOI: 10.1002/rcm.7664

Zane Baird, Valentina Pirro, Stephen Ayrton, Adam Hollerbach, Cathleen Hanau, Karen Marfurt, Mary Foltz, R. Graham Cooks, and Michael Pugia, “Tumor Cell Detection by Mass Spectrometry Using Signal Ion Emission Reactive Release Amplification”, Anal. Chem., 88 (2016) 6971 - 6975 DOI: 10.1021/acs.analchem.6b02043

Xin Yan, Ryan M. Bain, Yafeng Li, Ran Qiu, Tawnya G. Flick and R. Graham Cooks, “Online Inductive Electrospray Ionization Mass Spectrometry as a Process Analytical Technology Tool To Monitor the Synthetic Route to Anagliptin” Org. Process Res. Dev., Article ASAP, (2016) DOI: 10.1021/acs.oprd.6b00039

R. Graham Cooks, “John H. Beynon (1923–2015)” J. Am. Soc. Mass Spectrom., 27 (2016) 561-562 DOI: 10.1007/s13361-016-1337-9

Depanjan Sarkar, Maheswari Kavirajan Mahitha, Anirban Som, Anyin Li, Michael Wleklinski, Robert Graham Cooks and Thalappil Pradeep,” Metallic Nanobrushes Made using Ambient Droplet Sprays”, Adv. Mater., 28 (2016) 2223–2228 DOI: 10.1002/adma.201505127

Thomas M. Annesley, R. Graham Cooks, David A. Herold and Andrew N. Hoofnagle, “Clinical Mass Spectrometry—Achieving Prominence in Laboratory Medicine”, Clin. Chem., 62 (2016) 1-3 DOI: 10.1373/clinchem.2015.251272

Christina R. Ferreira, Karen E. Yannell, Alan K. Jarmusch, Valentina Pirro, Zheng Ouyang and R. Graham Cooks, “Ambient Ionization Mass Spectrometry for Point-of-Care Diagnostics and Other Clinical Measurements”, Clin. Chem., 62 (2016) 99-110 DOI: 10.1373/clinchem.2014.237164

Pu Wei, Soumabha Bag, Christopher J. Pulliam, Dalton T. Snyder, Rafal M. Pielak and R. Graham Cooks, “Analysis of bacteria using zero volt paper spray”, Anal. Methods., 8 (2016) 1770-1773 DOI: 10.1039/C6AY00063K

Christopher J. Pulliam, Pu Wei, Dalton T. Snyder, Xiao Wang, Zheng Ouyang, Rafal M. Pielak and   R. Graham Cooks, “Rapid discrimination of bacteria using a miniature mass spectrometer”, Analyst., 141 (2016) 1633-1636 DOI: 10.1039/C5AN02575C

Qiang Ma, Hua Bai, Wentao Li, Chao Wang, Xinshi Li, R. Graham Cooks and Zheng Ouyang, “Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system”, Anal. Chim. Acta., 912 (2016) 65-73 DOI:10.1016/j.aca.2016.01.031

Dalton T. Snyder, Christopher J. Pulliam, Zheng Ouyang and R. Graham Cooks, “Miniature and Fieldable Mass Spectrometers: Recent Advances”, Anal Chem., 88 (2016) 2-29 DOI: 10.1021/acs.analchem.5b03070

Ryan M. Bain, Christopher J. Pulliam, Shannon A. Raab and R. Graham Cooks, “Chemical Synthesis Accelerated by Paper Spray: The Haloform Reaction”, J. Chem. Educ., 93 (2016) 340-344 DOI:10.1021/acs.jchemed.5b00263

Yafeng Li, Xin Yan and R. Graham Cooks, “The Role of the Interface in Thin Film and Droplet Accelerated Reactions Studied by Competitive Substituent Effects”, Angew. Chem. Int. Ed., 55 (2016) 3433-3437 DOI: 10.1002/anie.201511352

Alan K. Jarmusch, Valentina Pirro, Zane Baird, Eyas M. Hattab, Aaron A. Cohen-Gadol, and R. Graham Cooks, “Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS” PNAS., 113 (2016) 1486–1491DOI: 10.1073/pnas.1523306113

Ryan M. Bain, Xin Yan, Shannon A. Raab, Stephen T. Ayrton, Tawnya G. Flick and R. Graham Cooks, “On-line chiral analysis using the kinetic method”, Analyst., 141 (2016) 2441 - 2446 DOI: 10.1039/C6AN00100A

2017

Stephen T. Ayrton, Rhys Jones, David S. Douce, Mike R. Morris and R. Graham Cooks “Uncatalyzed, Regioselective Oxidation of Saturated Hydrocarbons in an Ambient Corona Discharge” Angewandte Chemie (2017) https://doi.org/10.1002/anie.201711190

Dalton T. Snyder, Lucas J. Szalwinski and R. Graham Cooks “Simultaneous and Sequential MS/MS Scan Combinations and Permutations in a Linear Quadrupole Ion Trap” Anal. Chem. (2017) DOI: 10.1021/acs.analchem.7b03064

Valentina Pirro, Clint M. Alfaro, Alan K. Jarmusch, Eyas M. Hattab, Aaron A. Cohen-Gadol and R. Graham Cooks “Intraoperative assessment of tumor margins during glioma resection by desorption electrospray ionization-mass spectrometry” PNAS (2017) DOI: https://doi.org/10.1073/pnas.1706459114

Valentina Pirro, Raquel Sero Llor, Alan K. Jarmusch, Clint M. Alfaro, Aaron A. Cohen-Gadol, Eyas M. Hattab and R. Graham Cooks “Analysis of human gliomas by swab touch spray-mass spectrometry: applications to intraoperative assessment of surgical margins and presence of oncometabolites” Analyst (2017) DOI: 10.1039/C7AN01334E

Tianyang Guo, Zezhen Zhang, Karen E Yannell, Yiyang Dong and R. Graham Cooks“Paper spray ionization mass spectrometry for rapid quantification of illegal beverage dyes” Analytical Methods (2017) DOI: 10.1039/C7AY02241G

Patrick W. Fedick, Brandon J. Bills, Nicholas E. Manicke, and R. Graham Cooks “Forensic Sampling and Analysis from a Single Substrate for Surface-Enhanced Raman Spectroscopy followed by Paper Spray Mass Spectrometry” Analytical Chemistry (2017) DOI: 110.1021/acs.analchem.7b02798

Sebastiaan F. Teunissen, Patrick W. Fedick, Bjorn J. A. Berendsen, Michel W. F. Nielen, Marcos N. Eberlin, R. Graham Cooks, and Arian C. van Asten “Novel Selectivity-Based Forensic Toxicological Validation of a Paper Spray Mass Spectrometry Method for the Quantitative Determination of Eight Amphetamines in Whole Blood” JASMS (2017) DOI: 10.1007/s13361-017-1790-0

Karen E. Yannell, Katelynn Smith, Clint M. Alfaro, Alan K. Jarmusch, Valentina Pirro, R. Graham Cooks “N-Acetylaspartate and 2-Hydroxyglutarate Assessed in Human Brain Tissue by Mass Spectrometry as Neuronal Markers of Oncogenesis” Clinical Chemistry (2017) DOI: 10.1373/clinchem.2017.279364

Zhenwei Wei, Michael Wleklinski, Christina Ferreira, and R. Graham Cooks “Reaction Acceleration in Thin Films with Continuous Product Deposition for Organic Synthesis” Angewandte Chemie (2017) DOI: 10.1002/anie.201704520

H. Samuel Ewan, Kiran Iyer, Seok-Hee Hyun, Michael Wleklinski, R. Graham Cooks, and David H. Thompson “Multistep Flow Synthesis of Diazepam Guided by Droplet-Accelerated Reaction Screening with Mechanistic Insights from Rapid Mass Spectrometry Analysis” Org. Process Res. Dev. (2017) DOI: 10.1021/acs.oprd.7b00218

Fernanda B. Cordeiro1, Christina R. Ferreira1, Tiago Jose P. Sobreira, Karen E. Yannell, Alan K. Jarmusch, Agnaldo P. Cedenho, Edson G. Lo Turco, and R. Graham Cooks “Multiple reaction monitoring (MRM)‐profiling for biomarker discovery applied to human polycystic ovarian syndrome” Rapid Commun Mass Spectrom. 31 (2017) 1462–1470. DOI: 10.1002/rcm.7927

Pengyuan Liu, Pengyi Zhao, R. Graham Cooks, and Hao Chen “Atmospheric pressure neutral reionization mass spectrometry for structural analysis” Chem. Sci. (2017) DOI: 10.1039/c7sc01999h

Dalton Snyder and R. Graham Cooks “Single Analyzer Neutral Loss Scans in a Linear Quadrupole Ion Trap Using Orthogonal Double Resonance Excitation” Anal. Chem. (2017) DOI: 10.1021/acs.analchem.7b01963

Patrick W. Fedick, Ryan M. Bain, Kinsey Bain, and R. Graham Cooks “Chiral Analysis by Tandem Mass Spectrometry Using the Kinetic Method, by Polarimetry, and by 1H NMR Spectroscopy” J Chem Ed. (2017) DOI: 10.1021/acs.jchemed.7b00090

Ryan M. Bain, Stephen T. Ayrton, and R. Graham Cooks “Fischer Indole Synthesis in the Gas Phase, the Solution Phase, and at the Electrospray Droplet Interface” JASMS (2017) DOI: 10.1007/s13361-017-1597-z

Caitlin Falcone, Zinia Jaman, Michael Wleklinski, Andy Koswara, David H. Thompson, and R. Graham Cooks “Reaction screening and optimization of continuous-flow atropine synthesis by preparative electrospray mass spectrometry” Analyst 142 (2017) 2836 DOI: 10.1039/C7AN00622E

Xin Li, Xin Yan, and R. Graham Cooks “Functionalization of saturated hydrocarbons using nitrogen ion insertion reactions in mass spectrometry”, IJMS 418 (2017) 79 https://doi.org/10.1016/j.ijms.2016.11.017

Dalton T. Snyder, Desmond A. Kaplan, Ryan M. Danell, Friso H. W. van Amerom, Veronica T. Pinnick, William B. Brinckerhoff, Paul R. Mahaffy, and R. Graham Cooks “Unique capabilities of AC frequency scanning and its implementation on a Mars Organic Molecule Analyzer linear ion trap”, Analyst 142 (2017) 2109 DOI: 10.1039/c7an00664k

Dalton Snyder and R. Graham Cooks “Single Analyzer Precursor Ion Scans in a Linear Quadrupole Ion Trap Using Orthogonal Double Resonance Excitation”, JASMS, (2017) DOI: 10.1007/s13361-017-1707-y

Christopher J. Pulliam, Ryan M. Bain, Heather L. Osswald, Dalton T. Snyder, Patrick W. Fedick, Stephen T. Ayrton, Tawnya G. Flick, and R. Graham Cooks “Simultaneous On-line Monitoring of Multiple Reactions using a Miniature Mass Spectrometer”, Analytical Chemistry,  (2017)  DOI: 10.1021/acs.analchem.7b00119

Dalton Snyder and R. Graham Cooks “Improving mass assignments in quadrupole ion traps operated using ac scans: Theory and experimental validation”, IJMS, 668 (2017) 69-89 DOI: https://doi.org/10.1016/j.ijms.2017.05.001

R. Graham Cooks “Jonathan W. Amy and the Amy Facility for Instrumentation Development” Analytical Chemistry, (2017)DOI: 10.1021/acs.analchem.7b00158

Patrick W Fedick, Ryan M Bain, Shunshun Miao, Valentina Pirro, and R. Graham Cooks “State-of-the-Art Mass Spectrometry for Point-of-Care and other Applications: A Hands-on Intensive Short Course for Undergraduate Students” IJMS 417 (2017) 22 DOI: 10.1016/j.ijms.2017.04.008

Bradley P. Loren, Michael Wleklinski, Andy Koswara, Kathryn Yammine, Yanyang Hu, Zoltan K. Nagy, David H. Thompson, and R. Graham Cooks “Mass Spectrometric Directed System for the Continuous-Flow Synthesis and Purification of Diphenhydramine” Chemical Science, 8 (2017) 4363 DOI: 10.1039/C7SC00905D

Adam Hollerbach, Zane Baird, and R. Graham Cooks “Ion Separation in Air Using a Three-Dimensional Printed Ion Mobility Spectrometer”, Analytical Chemistry, (2017) DOI: 10.1021/acs.analchem.7b00469

Dalton Snyder, Wen-Ping Peng, and R. Graham Cooks “Resonance Methods in Quadrupole Ion Traps”, Chemical Physics Letters, 668 (2017) 69-89 DOI: http://dx.doi.org/10.1016/j.cplett.2016.11.011

Karen E. Yannell, Kristina R. Kesely, Huynh Dinh Chien, Candice B. Kissinger, and R. Graham Cooks “Comparison of paper spray mass spectrometry analysis of dried blood spots from devices used for in-field collection of clinical samples”, Anal Bioanal Chem., 409 (2017) 121 DOI:10.1007/s00216-016-9954-5

Valentina Pirro, Alan K Jarmusch, Clint M Alfaro, Eyas M. Hattab, Aaron A Cohen-Gadol, and R. Graham Cooks “Utility of neurological smears for intrasurgical brain cancer diagnosis and tumor cell concentration by DESI-MS” Analyst (2017)DOI: 10.1039/C6AN02645A

2018

Dalton T. Snyder, Lucas J. Szalwinski, and R. Graham Cooks “Mass Spectrometry | Ion Traps” in Reference Module in Chemistry, Molecular Sciences and Chemical Engineering (2018) DOI: 10.1016/B978-0-12-409547-2.14521-4

Hong Zhang, Zhenwei Wei, Jie Jiang, and R. Graham Cooks “Nebulization en Route to Isolate, Ionize, Dissociate and Characterize the Neutral Serine Octamer” Angew. Chem. Int. Ed. (2018) DOI: 10.1002/anie.201811098

Camila B. de Lima, Christina R. Ferreira, Marcella P. Milazzotto, Tiago J. P. Sobreira, Alessandra A. Vireque, and R. Graham Cooks “Comprehensive Lipid Profiling of Early Stage Oocytes and Embryos by MRM Profiling” Journal of Mass Spectrometry (2018) DOI: 10.1002/jms.4301

Dalton T. Snyder, Lucas J. Szalwinski, Mitch Wells, and R. Graham Cooks “Logical MS/MS Scans: A New Set of Operations for Tandem Mass Spectrometry” Analyst (2018) DOI: 10.1039/c8an01661e

Adam Hollerbach, Patrick W. Fedick, and R. Graham Cooks “Ion Mobility-Mass Spectrometry using a Dual-Gated 3D printed Ion Mobility Spectrometer” Anal. Chem. (2018) DOI: 10.1021/acs.analchem.8b02209

Ryan M. Bain, Patrick W. Fedick, Jonathan M. Dilger, and R. Graham Cooks “Analysis of Residual Explosives by Swab Touch Spray Ionization Mass Spectrometry” Propellants, Explosives, Pyrotechnics (2018) DOI: 10.1002/prep.201800122

Karen E. Yannell, Christina R. Ferreira, Shane E. Tichy and R. Graham Cooks “Multiple reaction monitoring (MRM)-profiling with biomarker identification by LC-QTOF to characterize coronary artery disease” Analyst (2018) DOI: 10.1039/c8an01017j

Pengyu Zhao, Travis White, R. Graham Cooks, Qinghao Chen, Yong Liu, and Hao Chen “Detection of Neutral CO Lost During Ionic Dissociation Using Atmospheric Pressure Thermal Dissociation Mass Spectrometry (APTD-MS)” JASMS (2018) DOI: 10.1007/s13361-018-2055-2

Cedric D'Hue, Deepika Dhawan, Tyler Peat, José Ramos-Vara, Alan Jarmusch, Deborah W. Knapp, and R. Graham Cooks “Fatty Acid Patterns Detected by Ambient Ionization Mass Spectrometry in Canine Invasive Urothelial Carcinoma From Dogs of Different Breeds” Bladder Cancer (2018) DOI: 10.3233/BLC-170125

Zhenwei Wei, Xiao-Chao Zhang, Jinyu Wang, Sichun Zhang, Xinrong Zhang, and R. Graham Cooks “High Yield Accelerated Reactions in Nonvolatile Microthin Films: Chemical Derivatization for Analysis of Single-Cell Intracellular Fluid” Chem. Sci. (2018) DOI: 10.1039/C8SC03382J

Xingshuo Chen, and R. Graham Cooks “Accelerated reactions in field desorption mass spectrometry” J. Mass Spectrom. (2018) DOI: 10.1002/jms.4254

Alan K. Jarmusch, Valentina Pirro, David L. Logsdon, and R. Graham Cooks “Direct Ion Generation from Swabs” Talanta (2018) DOI: 10.1016/j.talanta.2018.02.105

Xin Yan and R. Graham Cooks “Mass Spectrometry for Synthesis and Analysis ” Annual Review of Analytical Chemistry (2018) DOI: 10.1146/annurev-anchem-061417-125820

Patrick Fedick, Ryan Bain, Kinsey Bain, Tsdale Mehari, and R. Graham Cooks “Accelerated tert-Butyloxycarbonyl Deprotection of Amines in Microdroplets Produced by a Pneumatic Spray ” International Journal of Mass Spectrometry (2018) DOI: 10.1016/j.ijms.2018.05.009

Yangjie Li, Yong Liu, Hong Gao, Roy Helmy, W Peter Wuelfing, Christopher Welch and R. Graham Cooks “Accelerated Forced Degradation of Pharmaceuticals in Levitated Microdroplet Reactors” Chemistry - A European Journal (2018) DOI: 10.1002/chem.201801176

Michael Wleklinski, Bradley P. Loren, Christina R. Ferreira, Zinia Jaman, Larisa Avramova, Tiago J. P. Sobreira, David H. Thompson and R. Graham Cooks “High throughput reaction screening using desorption electrospray ionization mass spectrometry” Chem. Sci. (2018) DOI: 10.1039/C7SC04606E

Stephen T. Ayrton, Xingshuo Chen, Ryan M. Bain, Christopher J. Pulliam, Michal Achmatowicz, Tawnya Flick, Da Ren, and R. Graham Cooks “Gas Phase Ion Chemistry to Determine Isoaspartate in a Peptide Backbone” JASMS (2018) DOI: 10.1007/s13361-018-1923-0

Dalton T. Snyder, Lucas J. Szalwinski, Ryan Hilger and R. Graham Cooks “Implementation of Precursor and Neutral Loss Scans on a Miniature Ion Trap Mass Spectrometer and Performance Comparison to a Benchtop Linear Ion Trap” JASMS (2018) DOI: 10.1007/s13361-018-1922-1

Dalton T. Snyder, Lucas J. Szalwinski, Robert L. Schrader, Valentina Pirro, Ryan Hilger and R. Graham Cooks “Precursor and Neutral Loss Scans in an RF Scanning Linear Quadrupole Ion Trap” JASMS (2018) DOI: 10.1007/s13361-018-1920-3

Zezhen Zhang, Christopher J. Pulliam, Tawnya Flick and R. Graham Cooks “Electrophoretic Desalting To Improve Performance in Electrospray Ionization Mass Spectrometry” Anal. Chem. (2018) DOI: 10.1021/acs.analchem.7b04529

Adam Hollerbach, David Logsdon, Kiran Iyer, Anyin Li, J. Andy Schaber and R. Graham Cooks “Sizing sub-diffraction limit electrosprayed droplets by structured illumination microscopy” Analyst 143 (2018) 232–240. DOI: 10.1039/c7an01278k

Hannah Marie Brown, Valentina Pirro and R. Graham Cooks “From DESI to the MasSpec Pen: Ambient Ionization Mass Spectrometry for Tissue Analysis and Intrasurgical Cancer Diagnosis” Clinical Chemistry (2018) DOI: 10.1373/clinchem.2017.281923

Cedric D'Hue, Michael Moore, Don-John Summerlin, Alan Jarmusch, Clint Alfaro, Avinash Mantravadi, Arnaud Bewley, D. Gregory Farwel and R. Graham Cooks “Feasibility of desorption electrospray ionization mass spectrometry for diagnosis of oral tongue squamous cell carcinoma” RCM (2018) DOI: 10.1002/rcm.8019

Kiran Iyer, Jing Yi, Andrew Bogdan, Nari Talaty, Stevan W. Djuric and R. Graham Cooks “Accelerated multi-reagent copper catalysed coupling reactions in micro droplets and thin films” React. Chem. Eng. (2018) DOI: 10.1039/C8RE00002F

2019

Hannah Marie Brown, Fan Pu, Mahua Dey, James Miller, Mitesh V. Shah, Scott A. Shapiro, Zheng Ouyang, Aaron A. Cohen-Gadol, and R. Graham Cooks “Intraoperative detection of isocitrate dehydrogenase mutations in human gliomas Using a miniature mass spectrometers” Anal. Bioanal. Chem. (2019) DOI: 10.1007/s00216-019-02198-y

Kiran Iyer, Brett M. Marsh, Grace O. Capek, Robert L. Schrader, Shane Tichy, and R. Graham Cooks “Ion Manipulation in Open Air Using 3D-Printed Electrodes” JASMS (2019) DOI: 10.1007/s13361-019-02307-2

Bradley P. Loren, H. Samuel Ewan, Larisa Avramova, Christina R. Ferreira, Tiago J. P. Sobreira, Kathryn Yammine, Huiying Liao, R. Graham Cooks, and David H. Thompson “High Throguhput Experimentation Using DESI-MS to Guide Continuous-Flow Synthesis” Sci. Rep. (2019) DOI: 10.1038/s41598-019-50638-7

Zhenwei Wei, Zhuoer Xie, Reshma Kuvelkar, Vinit Shah, Kevin Bateman, David G. McLaren, and R. Graham Cooks “High-throughput bioassays using ‘dip-and-go’ multiplexed electrospray mass spectrometry” Angew. Chem. Int. Ed. (2019) DOI: 10.1002/anie.201909047

Dalton T. Snyder, Lucas J. Szalwinski, Zachary St. John, and R. Graham Cooks “Two-dimensional tandem mass spectrometry in a single scan on a linear quadrupole ion trap” Anal. Chem. (2019) DOI: 10.1021/acs.analchem.9b03123

Brett M. Marsh, Kiran Iyer, and R. Graham Cooks “Reaction Acceleration in Electrospray Droplets: Size, Distance, and Surfactant Effects” JASMS (2019) DOI: 10.1007/s13361-019-02264-w

Zhuoer Xie, L. Edwin Gonzalez, Christina R. Ferreira, Anna Vorsilak, Dylan Frabutt, Tiago J. P. Sobreira, Michael Pugia, and R. Graham Cooks “Multiple Reaction Monitoring Profiling (MRM-Profiling) of Lipids to Distinguish Strain-Level Differences in Microbial Resistance in Escherichia coli” Anal. Chem. (2019) DOI: 10.1021/acs.analchem.9b02465

Patrick W. Fedick, Kiran Iyer, Zhenwei Wei, Larisa Avramova, Grace O. Capek, and R. Graham Cooks “Screening of the Suzuki Cross-Coupling Reaction Using Desorption Electrospray Ionization in High-Throughput and in Leidenfrost Droplet Experiments” JASMS (2019) DOI: 10.1007/s13361-019-02287-3

Robert L. Schrader, Stephen T. Ayrton, Andreas Kaerner, and R. Graham Cooks “High-Throughput, Low-Cost Reaction Screening using a Modified 3D Printer” Analyst (2019) DOI: 10.1039/C9AN00785G

Dalton T. Snyder, Paul S. Demond, Lucas J. Szalwinski, Elizabeth S. Dhummakupt, Ethan M. McBride, R. Graham Cooks, Trevor Glaros, and Phillip M. Mach “Two-dimensional MS/MS scans on a linear ion trap mass analyzer: Identification of V-Series chemical warfare agents” Int. J. Mass Spectrom. (2019) DOI: 10.1016/j.ijms.2019.06.007

Marisol León, Christina R. Ferreira, Livia S. Eberlin, Alan K. Jarmusch, Valentina Pirro, Aná Clara Bastos Rodrigues, Phelipe Oliveira Favaron, Maria Angelica Miglino, and R. Graham Cooks “Metabolites and Lipids Associated with Fetal Swine Anatomy via Desorption Electrspray Ionization - Mass Spectrometry Imaging” Sci. Rep. (2019) DOI: 10.1038/s41598-019-43698-2

Nicolas Mauricio Morato, Valentina Pirro, Patrick W. Fedick, and R. Graham Cooks “Quantitative Swab Touch Spray Mass Spectrometry for Oral Fluid Drug Testing” Anal. Chem. (2019) DOI: 10.1021/acs.analchem.9b01637

Dalton T. Snyder, Lucas J. Szalwinski, Alice L. Pilo, Nina K. Jarrah, and R. Graham Cooks “Selective Gas-Phase Mass Tagging via Ion/Molecule Reactions Combined with Single Analyzer Neutral Loss Scans to Probe Pharmaceutical Mixtures ” JASMS (2019) DOI: 10.1007/s13361-019-02149-y

Zinia Jaman, Tiago J. P. Sobreira, Ahmed Mufti, Christina R. Ferreira, R. Graham Cooks, and David H. Thompson “Rapid On-Demand Synthesis of Lomustine under Continuous Flow Conditions ” Org. Process Res. Dev. (2019) DOI: 10.1021/acs.oprd.8b00387

Fan Pu, Clint M. Alfaro, Valentina Pirro, Zhuoer Xie, Zheng Ouyang, and R. Graham Cooks “Rapid determination of isocitrate dehydrogenase mutation status of human gliomas by extraction nanoelectrospray using a miniature mass spectrometer ” Anal. Bioanal. Chem. (2019) DOI: 10.1007/s00216-019-01632-5

Felix Leung, Livia S. Eberlin, Kristina Schwamborn, Ron M. A. Heeren, Nicolas Winograd, and R. Graham Cooks “Mass Spectrometry-Based Tissue Imaging: The Next Frontier in Clinical Diagnostics?” Clin. Chem. (2019) DOI: 10.1373/clinchem.2018.289694

Robert L. Schrader, Patrick W. Fedick, Tsdale F. Mehari, and R. Graham Cooks “Accelerated Chemical Synthesis: Three Ways of Performing the Katritzky Transamination Reaction” J. Chem. Educ. (2019) DOI: 10.1021/acs.jchemed.8b00658

Patrick W. Fedick, Robert L. Schrader, Stephen T. Ayrton, Christopher J. Pulliam, and R. Graham Cooks “Process Analytical Technology for Online Monitoring of Organic Reactions by Mass Spectrometry and UV−Vis Spectroscopy” J. Chem. Educ. (2019) DOI: 10.1021/acs.jchemed.8b00725

Clint M. Alfaro, Valentina Pirro, Michael F. Keating, Eyas M. Hattab, R. Graham Cooks, and Aaron A. Cohen-Gadol “Intraoperative assesment of isocitrate dehydrogenase mutation status in human gliomas using desorption electrspray ionization—mass spectrometry” J. Neurosurg. (2019) DOI: 10.3171/2018.8.JNS181207